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Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo

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It is FDA-approved for clinical use and stimulates endogenous GH secretion

Since there are obvious differences between rodent and human physiology, it cannot be ignored that this may have a significant impact on the efficacy and safety of (any) novel agents

HondaS.et al.1995Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: implication as neurotrophic factor, 37